AVM develops split butterfly valve solutions for pharmaceutical powder handling and high-containment process systems. The OEB4 and OEB5 configurations are designed for GMP-compliant applications involving HPAPI and other highly potent powders with very low Occupational Exposure Limits (OELs). The system can be applied to powder transfer, charging, discharging, sampling, and material handling processes where controlled connection between process equipment is required.
Containment level is a key consideration when handling highly potent pharmaceutical compounds. AVM provides OEB4 and OEB5 testing reports to help buyers evaluate the containment performance of the equipment against their process requirements. This makes the Split Butterfly Valve suitable for pharmaceutical facilities working with different levels of powder potency and containment requirements.
Cleaning and sterilization procedures can directly affect equipment selection in pharmaceutical production. AVM SBV supports both CIP and SIP systems, allowing the valve to be integrated into automated cleaning and sterilization processes. This can simplify equipment validation and reduce the need for frequent manual intervention during routine production cycles.
For aseptic and high-containment processing, sterilization compatibility is an important part of system design. AVM split butterfly valve solutions are compatible with 134°C autoclave sterilization and VHP decontamination. These options provide manufacturers with greater flexibility when designing sterilization procedures for different production environments.
The performance of a split valve system also depends on the accessories used during connection, transfer, washing, and protection. AVM supplies active plungers, passive protectors, passive openers, washing caps, compensators, and wash lance lifters. These components can be selected according to the equipment configuration and operating procedure, helping create a complete powder handling and connection system.
For applications requiring disposable material transfer solutions, AVM can supply single-use Beta Bags in different sizes and volumes. The bags can be combined with the Split Butterfly Valve system according to the required material capacity and process configuration, providing an option for facilities looking to simplify material handling and reduce cleaning requirements associated with reusable transfer containers.
AVM SBV solutions can be integrated into isolators and RABS, reactors, roto cone vacuum dryers, and powder filling lines. These applications typically require controlled powder connection and transfer between processing equipment. The Split Butterfly Valve provides a practical interface for transferring high-potency powders while supporting the cleaning, sterilization, and containment requirements of pharmaceutical production.
AVM Extraordinary Intelligent Control Co., Ltd. is located in Wenzhou, China, and specializes in the design and manufacture of sanitary and containment valve systems. Its products are developed for demanding pharmaceutical and clean-process environments, with a focus on GMP-oriented design and high-containment applications. AVM holds ISO 9001, CE, and FDA certifications, providing international buyers with additional references for quality and compliance evaluation.
For pharmaceutical projects requiring an Split Butterfly Valve, AVM can provide OEB4 and OEB5 testing documentation, CIP/SIP-compatible configurations, sterilization options, connection accessories, and single-use Beta Bags according to the process requirements.
