The AVM Sterile Contamination-Free Beta Transfer Container RTP is tailored for clean and controlled environments, serving as a portable terminal for the RTP system. The device can dock with standard Alpha ports on isolators, glove boxes, and sealed chambers, utilizing a mature Alpha-Beta docking structure to create a completely sealed channel before operation.
During the transfer process, the Beta container and Alpha port hatch are linked seamlessly, ensuring no material exposure and no risk of personnel contact with contaminants throughout the entire process. The hatch automatically locks after the operation, maintaining a sealed integrity before and after separation, effectively solving problems such as cross-contamination, sterility failure, and material loss associated with traditional transfer methods. As a core piece of equipment developed in-house by a seasoned manufacturer, the product balances lightweight operation with high strength and durability, adaptable to various industrial production and laboratory scenarios.
The Sterile Contamination-Free Beta Transfer Container RTP employs an integrated sealed structure, maintaining a sterile and sealed state throughout the entire operation. This not only blocks external contaminants and protects the purity of raw materials and finished products but also prevents the leakage of high-risk powders and active materials, comprehensively ensuring the safety of personnel and the workshop environment.
Compatible with industry-standard RTP Alpha ports, covering all sizes from DN105 to DN460. Precise docking and stable locking ensure repeated sealing operations without requiring modifications to existing equipment, making it suitable for various cleanroom facilities.
Built-in mechanical interlock mechanism effectively prevents accidental opening, misalignment, and unauthorized operation. The door can only be opened after a fully and precisely locked connection, mitigating process risks at the hardware level and improving production safety and stability.
Offers two material options: 316L stainless steel, corrosion-resistant and resistant to repeated sterilization, suitable for high-frequency, high-intensity industrial production; and high-performance polymer material, lightweight and easy to handle, reducing manual labor and suitable for small-batch precision transport scenarios in laboratories.
The equipment features a smooth interior and exterior with minimal gaps, and its hygienic structure facilitates rapid cleaning, sterilization, and compliance verification, effectively reducing downtime and maintenance costs, and adapting to routine GMP-compliant production.
Utilizing an ergonomically optimized design with reasonable weight distribution, docking and handling operations are simple, significantly reducing the difficulty of daily operations and the probability of operational errors, thus improving operational efficiency.
Capable of transferring raw materials, finished pharmaceutical products, experimental samples, and production tools, while also supporting the closed-loop transfer of high-risk waste, comprehensively covering the material handling needs of aseptic pharmaceutical manufacturing, high-density manufacturing, and biological experiments.
The AVM Beta Transfer Container establishes a sterile transport channel without exposure through standard Alpha-Beta closed-loop docking. The operation process is standardized and traceable, with the following specific steps:
Align the Beta container with the corresponding Alpha port to complete the mechanical interlock.
The system automatically verifies the docking status. Upon compliance, the dual-door linkage access is unlocked.
Both doors open simultaneously, forming a sealed channel for safe material transfer.
After transfer, both doors lock. Once the seal is confirmed to be intact, the doors are unlocked and the equipment removed, maintaining a sterile state throughout the process.
The Sterile Contamination-Free Beta Transfer Container RTP is widely used in aseptic transport of pharmaceutical raw materials, aseptic preparation production, laboratory sampling and transfer, bioprocess culture, isolator/glove box operations, and closed-loop material transport in cleanrooms.
To comply with the new GMP standards, the aseptic API workshop of North China Pharmaceutical Group introduced the AVM Sterile Contamination-Free Beta Transfer Container RTP system for closed-loop transfer of highly active aseptic powder raw materials. The workshop's original transfer method suffered from issues such as material exposure, cross-contamination, and difficulties in validation, failing to meet the requirements of high-end aseptic production.
After implementing this equipment, the workshop could achieve fully enclosed aseptic transfer of raw materials, samples, and tools between the clean area and the isolator without modifying the existing isolator system. The 316L stainless steel body withstands repeated high-temperature sterilization, and the mirror-smooth structure facilitates rapid cleaning and validation, fully complying with GMP regulations. After implementation, the workshop's material contamination risk was significantly reduced, product qualification rate was significantly improved, and equipment downtime was reduced by more than 30%. Simultaneously, it completely eliminated the safety hazards of personnel contact with high-risk materials, becoming a typical application case of RTP closed-loop transfer in the domestic pharmaceutical industry.
| Parameter Item | Detailed Specifications |
| Applicable Port Sizes | Full series: DN105, DN190, DN270, DN350, DN460 |
| Main Materials | 316L Stainless Steel, High-Performance Polymer |
| Surface Finish | Ra ≤ 0.4 μm (Hygienic Mirror Polishing) |
| Core Performance | Sterile containment, cross-contamination prevention, mechanical interlock for anti-misoperation, chemical corrosion resistance, reusable after repeated sterilization |
| Compliance Standard | Compliant with GMP pharmaceutical production industry standards |
Yes. AVM Beta transport containers strictly adhere to the industry-standard RTP interface, providing full compatibility with mainstream brand Alpha ports without customization. They offer stable connection, strong versatility, and suitability for upgrades to both new and existing production lines.
For high-frequency industrial production, repeated sterilization, intense chemical cleaning, and high-risk material scenarios, the 316L stainless steel model is preferred due to its durability, corrosion resistance, and long-term reusability. For low-frequency, lightweight laboratory operations, the high-performance polymer model is recommended, offering portability, ease of use, and better cost-effectiveness.
Fully yes. AVM Beta transport containers are designed according to GMP principles. Their hygienic, seamless structure allows for successful cleaning, sterilization, and airtightness validation. Complete technical documentation is provided, easily passing compliance audits and quality control validations by pharmaceutical companies and biological laboratories.
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